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Related diseases are conditions that have similar signs and symptoms. A health care provider may consider these conditions in the table below when making a diagnosis.
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The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
Questions sent to GARD may be posted here if the information could be helpful to others. We remove all identifying information when posting a question to protect your privacy. If you do not want your question posted, please let us know. Submit a new question. I'm looking to find information on fumaric aciduria. Is there anyone living with this disease anywhere in the world?
See answer. National Institutes of Health. COVID is an emerging, rapidly evolving situation. Menu Search Home Diseases Fumarase deficiency. You can help advance rare disease research! This site is in-development and may not reflect the final version.
Preview the new GARD site. Views Read View source View history. Yolo Donate. Donate Contact us Guidelines Recent changes Open source. Network YouTube Good vibes. Most frequent English dictionary requests: , -1k , -2k , -3k , -4k , -5k , -7k , k , k , k , k , k , k , k Most frequent Greek dictionary requests: , -1k , -2k , -3k , -4k , -5k , -7k , k , k , k , k , k , k , k.
Please click on the reason for your vote: This is not a good example for the translation above. The wrong words are highlighted. Crystal structures of fumarase C revealed that the enzyme has two dicarboxylate binding sites; one was called the A site, and the second, the B site. This raises the question: which of the two sites is the active site of the enzyme? The A site shows relatively little change upon substrate binding, while the B site shifts substantially.
But these changes could account for regulation In order to answer this question, an experiment that tested each of the sites independently was conducted.
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